8/5/2023 0 Comments Soundwaves orgWith no way to consistently and accurately monitor the noise, NICU staff personally reminded staff, parents and visitors to lower their voices or take their conversations away from the babies' bedsides – a hard request when families want and need to be close. Hospital staff, parents and visitors, mechanical and medical equipment, maintenance, housekeeping, and numerous other sources all create noise. The SOS was obtained from the measurements.Neonatologist Derrick Rollo, DO, knows too well the detrimental effects of noise on premature infants. A B-mode ultrasound was used to guide the placement of our push beam focal point onto the bone surface underneath the skin layer (Figure 1b). An ultrasound probe and hydrophone were placed along the volunteers’ tibia bone (Figure 1a). Our cohort consisted of clinically confirmed osteopenia and osteoporosis patients, as well as normal volunteers without a history of bone fractures. Under an approved protocol by the Mayo Clinic Institutional Review Board (IRB), human volunteers were recruited to undergo our noninvasive bone assessment technique. This work demonstrates the feasibility of evaluating bone mechanical properties from sound waves due to bone vibrations. The radiate sound wave due to these vibrations are captured and used to analyze the bone mechanical properties. This will minimize the effects of the soft tissue. Thus, we propose utilizing a high intensity ultrasonic wave known as a “push beam” to exert a force on the bone surface thereby generating vibrations. The determination of the SOS parameter is susceptible to the amount of soft tissue between the skin surface and the bone. Speed of sound (SOS) measurements of the received ultrasonic signal is used to characterize the bone material properties. QUS utilizes measurements of ultrasonic waves between a transmitting and a receiving transducer aligned in parallel along bone surface. QUS has been sought as a nonionizing and noninvasive alternative to DEXA. This can be problematic for frequent clinical visits to monitor the efficacy of prescribed medications and therapies. However, DEXA uses ionizing radiation for imaging thus exposing patients to very low radiation doses. DEXA is the leading clinical bone quality assessment tool, detecting small changes in bone mineral content and density. As we age through adulthood, reductions in our bone mass increases due an unbalance activity in the bone reformation process leading to bone diseases such as osteoporosis putting a person at risk for fractures in the neck, hip and forearm areas.Ĭurrently bone assessment tools include dual-energy X-ray absorptiometry (DEXA), and quantitative ultrasound (QUS). Annually, approximately fifty percent of the 550,000 premature newborn infants in the United States suffer from bone metabolism related disorders such as osteopenia, which affect the bone development process into childhood. The assessment of the human skeletal health condition is of great importance ranging from newborn infants to the elderly. Presented Tuesday morning, May 24, 2016, 9:00 AM in Snowbird/Brighton room Popular version of paper 2aBAa5, “Bone demineralization assessment using acoustic radiation force” Leighton Wan – Cheong – Fatemi – Alizad – 50
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